ABCA13 Polyclonal antibody

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  WB analysis using 19764-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 19764-1-AP (ABCA13 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

ABCA13 Polyclonal Antibody for WB, ELISA

Cat No. 19764-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

ABCA13

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Tested Applications

• Positive WB detected in: HEK-293 cells, HeLa cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

19764-1-AP targets ABCA13 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: ATP-binding cassette, sub-family A (ABC1), member 13
• Calculated Molecular Weight: 576 kDa
• Observed Molecular Weight: 576 kDa
• GenBank Accession Number: NM_152701
• Gene Symbol: ABCA13
• Gene ID (NCBI): 154664
• RRID: AB_3669314
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q86UQ4
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ABCA13 belongs to the ABC transporter superfamily. ABCA13 is a transmembrane protein with the typical structure of ABC proteins: two transmembrane domains and two nucleotide-binding domains. ABCA13 may mediate the cholesterol and gangliosides transport from the plasma membrane to intracellular vesicles in an ATP hydrolysis-dependent manner, thus playing a role in their internalization by endocytic retrograde transport (PMID: 33478937). ABCA13 is expressed in the human trachea, testis, and bone marrow(PMID:12697998).