• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Recombinant Mouse CD44 protein (rFc Tag) (HPLC verified)

Species

Mouse

Purity

>90 %, SDS-PAGE
>90 %, SEC-HPLC

Tag

rFc Tag

Activity

not tested

Cat no : Eg3159

Validation Data Gallery

  • Purity of Recombinant Mouse CD44 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse CD44 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Mouse CD44 was greater than 90% as determined by SEC-HPLC.

    The purity of Mouse CD44 was greater than 90% as determined by SEC-HPLC.

Product Information

Purity >90 %, SDS-PAGE
>90 %, SEC-HPLC
Endotoxin <0.1 EU/μg protein, LAL method
Activity 
Not tested
Expression HEK293-derived Mouse CD44 protein Gln25-Thr224 (Accession# A2APM2) with a rabbit IgG Fc tag at the C-terminus.
GeneID 12505
Accession A2APM2
PredictedSize 48.2 kDa
SDS-PAGE 60-75 kDa, reducing (R) conditions
Formulation Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
Reconstitution Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
Storage Conditions
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

CD44 is a cell surface adhesion receptor that plays a crucial role in various biological processes, including cell-cell interactions, cell-matrix adhesion, cell migration, and signaling. It serves as a receptor for hyaluronan (HA) and has been implicated in several other ligand interactions, including osteopontin (OPN), collagens, and matrix metalloproteinases. CD44 is highly expressed in many cancers and is known to regulate metastasis by interacting with extracellular matrix ligands, promoting migration and invasion processes involved in metastases. It also has been identified as a marker for cancer stem cells and immune cells.

References:

1.Senbanjo LT. et al. (2017). Front Cell Dev Biol. 5:18.
2.Xu Y. et al. (2024). MedComm (2020). 5(6):e554. 
3.Xu H. et al. (2020). Exp Hematol Oncol. 9(1):36.