• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
Filter:
  • Western Blot (WB) analysis of various lysates using PTPRS Recombinant antibody (83833-5-RR)

    WB analysis using 83833-5-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 83833-5-RR (rPTPσ antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

  • Affinity and Kinetic Characterization of 83833-5-RR

    Affinity and Kinetic Characterization of 83833-5-RR

    Biolayer interferometry (BLl) kinetic assays of 83833-5-RR against Human PTPRS were performed. The affinity constant is 68.9 pM.

PTPRS Recombinant antibody

PTPRS Recombinant Antibody for WB, ELISA
Cat No. 83833-5-RR
Clone No.241005B6

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

Receptor-type tyrosine-protein phosphatase S, R PTP sigma, R PTP S, PTPSIGMA, EC:3.1.3.48

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

- +

Request bulk or custom quote

Please visit your regions distributor:

Tested Applications

Positive WB detected inA431 cells, SH-5Y5Y cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

83833-5-RR targets PTPRS in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Fusion Protein Predict reactive species
Full Name protein tyrosine phosphatase, receptor type, S
Calculated Molecular Weight217 kDa
Observed Molecular Weight140 kDa, 217 kDa
GenBank Accession NumberNM_002850
Gene Symbol PTPRS
Gene ID (NCBI) 5802
RRIDAB_3671416
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ13332
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Protein tyrosine phosphatase receptor type S (PTPRS, also known as R-PTP-S, PTPSIGMA, and R-PTP-sigma) is an integral membrane protein. It can promote oligomerization by binding to large heparan sulfate proteoglycan structures, and interact with NTRK1/3, PPFIA1/2/3 (PMID: 25385546; 8524829; 9624153). The non-glycosylated molecular weight of PTPRS is 214 kDa, and the extracellular domain can be cleaved near the cell membrane by an endoprotease to generate a glycated 140 kDa protein. Variations and mutations of PTPRS are associated with Alzheimer's disease and cholangiocarcinoma (PMID: 38766183; 35991009).

Protocols

Product Specific Protocols
WB protocol for PTPRS antibody 83833-5-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols