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PGF Recombinant antibody

PGF Uni-rAbTM Recombinant Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

ELISA

Conjugate

Unconjugated

CloneNo.

230532H3

Cat no : 83170-4-RR

Synonyms

D12S1900, PGF, PGFL, Placenta growth factor, placental growth factor, PLGF, PlGF 2, SHGC 10760

Validation Data Gallery

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  • Affinity and Kinetic Characterization of 83170-4-RR

    Affinity and Kinetic Characterization of 83170-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83170-4-RR against Human PGF were performed. The affinity constant is below 1 pM.

Product Information

83170-4-RR targets PGF in ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen PGF fusion protein Ag0969
Full Name placental growth factor
Calculated Molecular Weight 25 kDa
GenBank Accession NumberBC007789
Gene Symbol PGF
Gene ID (NCBI) 5228
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Placenta growth factor (PLGF) is also named as PGF and PGFL. PGF is a homodimeric glycoprotein, 46-50 kDa in size, belonging to the vascular endothelial growth factor (VEGF) sub-family. It plays an important role in pathological VEGF-driven angiogenesis. PLGF is expressed not only in placental cells but also in colon and mammary carcinomas. It acts as a primary inflammatory instigator of atherosclerotic plaque instability and thus may be useful as a risk-predicting biomarker in patients with acute coronary syndromes (ACS).