BBS4 Recombinant antibody
BBS4 Uni-rAbTM Recombinant Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
ELISA
Conjugate
Unconjugated
CloneNo.
230303E4
Cat no : 82961-3-RR
Synonyms
Validation Data Gallery
Product Information
82961-3-RR targets BBS4 in ELISA applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | BBS4 fusion protein Ag3430 |
| Full Name | Bardet-Biedl syndrome 4 |
| Calculated Molecular Weight | 519 aa, 58 kDa |
| GenBank Accession Number | BC027624 |
| Gene Symbol | BBS4 |
| Gene ID (NCBI) | 585 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
BBS4 (Bardet-Biedl syndrome protein 4) is one of the early BBS proteins discovered, with 35 mutations reported to cause the BBS phenotype (PMID: 26762677). BBS4 undergoes localization to the centriolar satellites of centrosomes and basal body of primary cilia, where it takes part in recruiting cargo to centriolar satellites and allowing the formation of a functional centrosomal microtubule organizing center (MTOC) (PMID: 25860617). Some research has found that BBS4 expression in humans during the development of CNS and sensory organs, concerning the cardinal clinical signs of BBS (PMID: 33860840).
