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  • Western Blot (WB) analysis of various lysates using OAS2 Recombinant antibody (82758-2-RR)

    WB analysis using 82758-2-RR

    IFN alpha treated A549 cells were subjected to SDS PAGE followed by western blot with 82758-2-RR (OAS2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

  • Western Blot (WB) analysis of various lysates using OAS2 Recombinant antibody (82758-2-RR)

    WB analysis using 82758-2-RR

    Jurkat cells were subjected to SDS PAGE followed by western blot with 82758-2-RR (OAS2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

OAS2 Recombinant antibody

OAS2 {ptg:Brand} Recombinant Antibody for WB, ELISA
Cat No. 82758-2-RR
Clone No.242801F11

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

EC:2.7.7.84, 2'-5'-oligoadenylate synthase 2, 2-5A synthase 2, 242801F11, (2-5')oligo(A) synthase 2

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Tested Applications

Positive WB detected inIFN alpha treated A549 cells, Jurkat cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

82758-2-RR targets OAS2 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen OAS2 fusion protein Ag6170 Predict reactive species
Full Name 2'-5'-oligoadenylate synthetase 2, 69/71kDa
Calculated Molecular Weight 82 kDa
Observed Molecular Weight 66-71 kDa
GenBank Accession NumberBC049215
Gene Symbol OAS2
Gene ID (NCBI) 4939
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP29728
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The 2-prime,5-prime oligoadenylate synthetases (OASs), such as OAS2, are IFN-induced proteins characterized by their capacity to catalyze the synthesis of 2-prime,5-prime oligomers of adenosine (2-5As). OAS2 is also named as p69 OAS / p71 OAS. It has 3 isoforms(71/69/20 kDa) produced by alternative splicing. The OAS2 isozymes are 69-71 kDa and form dimers(PMID:17765707). Glycosylation is essential for its activity(PMID:9880569). Constitutive expression of the 69-kDa form of the OAS2 protein in human cells inhibited the replication of encephalomyocarditis virus (EMCV) but not that of VSV, Sendai virus, or reovirus(PMID:16501108).

Protocols

Product Specific Protocols
WB protocol for OAS2 antibody 82758-2-RRDownload protocol
Standard Protocols
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