Product Information
68774-1-PBS targets CALCA/Calcitonin as part of a matched antibody pair:
MP50293-1: 68774-1-PBS capture and 68774-2-PBS detection (validated in Cytometric bead array)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CALCA/Calcitonin fusion protein Ag26141 Predict reactive species |
| Full Name | Calcitonin |
| Calculated Molecular Weight | 141 aa, 15 kDa |
| Observed Molecular Weight | 14 kDa |
| GenBank Accession Number | BC093753 |
| Gene Symbol | CALCA |
| Gene ID (NCBI) | 796 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P01258 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide, which is primarily localized to C and Aδ sensory fibers. These fibers display a wide innervation throughout the body, with extensive perivascular localization, and have a dual role in sensory (nociceptive) and efferent (effector) function. Discovered 30 years ago, it is produced as a consequence of alternative RNA processing of the calcitonin gene. CGRP has two major forms (α and β).
