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TRPV6 Polyclonal antibody

TRPV6 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 31045-1-AP

Synonyms

ABP/ZF, Calcium transport protein 1, CaT L, CaT like, CAT1, CATL, ECAC2, Epithelial calcium channel 2, HSA277909, LP6728, TRPV6, ZFAB

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using TRPV6 Polyclonal antibody (31045-1-AP)

    WB analysis using 31045-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 31045-1-AP (TRPV6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

Tested Applications

Positive WB detected inPC-3 cells, human placenta tissue, mouse brain tissue, mouse kidney tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

31045-1-AP targets TRPV6 in WB, ELISA applications and shows reactivity with Human, mouse samples.

Tested Reactivity Human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TRPV6 fusion protein Ag34052
Full Name transient receptor potential cation channel, subfamily V, member 6
Calculated Molecular Weight87KD
Observed Molecular Weight 75 kDa
GenBank Accession NumberNM_018646
Gene Symbol TRPV6
Gene ID (NCBI) 55503
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TRPV6, also named as CAT1 or ECaC2, is a member of the transient receptor potential (TRP) family of membrane proteins. Unlike most TRP channels, TRPV6 and its closest relative, TRPV5, are calcium-selective channels. TRPV6 is highly expressed in the proximal intestine, placenta and exocrine tissues (PMID: 12869611). It is probably involved in calcium absorption in various tissues, including calcium reabsorption in kidney. TRPV6 is overexpressed in some cancers and exhibits oncogenic potential.

Protocols

Product Specific Protocols
WB protocol for TRPV6 antibody 31045-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols