Anticorps Polyclonal de lapin anti-BMP2

• Phare
• Validé par KD/KO

BMP2 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain et plus (3)

Applications

WB, IF, IHC, ELISA

Conjugaison

Non conjugué

Publications

56

N° de cat : 18933-1-AP

Synonymes

BMP 2, BMP 2A, BMP2, BMP-2, BMP2A, bone morphogenetic protein 2, Bone morphogenetic protein 2A

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Galerie de données de validation

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  WB analysis of HeLa using 18933-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 18933-1-AP (BMP2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HeLa,

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 2 publications below
• WB: See 48 publications below
• IHC: See 13 publications below
• IF: See 6 publications below

Informations sur le produit

18933-1-AP cible BMP2 dans les applications de WB, IF, IHC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: rat, Humain, souris, Hamster
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: BMP2 Protéine recombinante Ag13501
• Nom complet: bone morphogenetic protein 2
• Masse moléculaire calculée: 396 aa, 44 kDa
• Numéro d’acquisition GenBank: BC069214
• Symbole du gène: BMP2
• Identification du gène (NCBI): 650
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.

Publications

Species	Application	Title
rat	WB,IHC	Biomaterials; Guided bone regeneration is promoted by the molecular events in the membrane compartment.; Authors - Alberto Turri
human	WB	Biomed Pharmacother; Bacitracin promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by stimulating the bone morphogenetic protein-2/Smad axis.; Authors - Hui Li ; KD Validated
human	WB	Carbohydr Polym; A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4.; Authors - Wucheng Wang
rat	WB,IHC	Int J Nanomedicine; The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway.; Authors - Guilan Zhang
rat	WB	Arterioscler Thromb Vasc Biol; Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.; Authors - Yun Zhou
rat	WB，IHC	Antioxid Redox Signal; Role of Nox4 in high calcium-induced renal oxidative stress damage and crystal deposition.; Authors - Yang Xun

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