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NeutraKine® IFN Alpha 2A Monoklonaler Antikörper

NeutraKine® IFN Alpha 2A Monoklonal Antikörper für Neutralization, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

Neutralization, ELISA

Konjugation

Unkonjugiert

CloneNo.

2H8G1

Kat-Nr. : 69008-1-Ig

Synonyme

IFN alpha 2, IFNA, IFNA2, IFN-alpha 2, INFA2, Interferon alpha 2, Interferon alpha A, interferon, alpha 2, LeIF A, NeutraKine® IFN Alpha 2A

Galerie der Validierungsdaten

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  • Neutralization experiment of NeutraKine® IFN Alpha 2A using NeutraKine® IFN Alpha 2A Monoclonal antibody (69008-1-Ig)

    Neutralization experiment of NeutraKine® IFN Alpha 2A using 69008-1-Ig

    Recombinant human IFN alpha 2A (Cat.NO. HZ-1066) inhibits the growth of TF-1 cell line (human erythroleukemic cell line) in a dose-dependent manner (blue curve, refer to bottom X-left Y). The activity of human IFN alpha 2A (100 ng/mL HZ-1066) is neutralized by mouse anti-human IFN alpha 2A monoclonal antibody 69008-1-Ig at serial dose (red curve, refer to top X-right Y). The ND50 is typically 300-500 ng/mL.

Neutralization

Produktinformation

69008-1-Ig bindet in Neutralization, ELISA NeutraKine® IFN Alpha 2A und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen human Humankine IFN Alpha 2A protein HZ-1066
Vollständiger Name interferon, alpha 2
Gene symbol IFNA2
Gene ID (NCBI) 3440
Konjugation Unkonjugiert
Form Lyophilized Powder
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer Sterile PBS.
Endotoxin<0.1 EU/μg
WiederherstellungThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Hintergrundinformationen

Interferon alpha 2 is a type 1 interferon. Interferon alpha 2 is secreted by virus-infected cells and inhibits other cells from further infection. Recombinant human interferon alpha 2 has been approved for therapeutic application in a range of human oncological and viral diseases. Three Interferon alpha 2 subvariants (2A, 2B, 2C) differ by only one or two amino acids at positions 23 and/or 34 of the mature protein (PMID: 25982860; 10672347; 1694761).

This antibody can be used to neutralize the bioactivity of Interferon alpha 2.