FPR2 Polyklonaler Antikörper

FPR2 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF, IHC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13448-1-AP

Synonyme

ALXR, FMLP R I, FMLP R II, FMLP related receptor I, FMLPX, formyl peptide receptor 2, Formyl peptide receptor like 1, FPR2, FPR2A, FPRH1, FPRH2, FPRL1, HM63, Lipoxin A4 receptor, LXA4 receptor, LXA4R, N formyl peptide receptor 2, RFP



Geprüfte Anwendungen

Produktinformation

13448-1-AP bindet in WB, IF, IHC, ELISA FPR2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
In Publikationen genannte Reaktivitäthuman, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FPR2 fusion protein Ag4282
Vollständiger Name formyl peptide receptor 2
Berechnetes Molekulargewicht 351 aa, 39 kDa
GenBank-ZugangsnummerBC029125
Gene symbol FPR2
Gene ID (NCBI) 2358
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The formyl peptide receptors (FPRs) are a group of G protein-coupled chemoattractant receptorsthat play important roles in host defense and inflammation (PMID: 28335409). In humans, three different isoforms are expressed (FPR1, FPR2, and FPR3). FPR2, also known as FPRL1 or ALX, is expressed by many cell types including monocytes, neutrophils, macrophages, astrocytoma cells, epithelial cells. FPR2 conveys the biological functions of a variety of ligands, including N-formyl-methionyl peptides, the proresolution mediators annexin A1 (AnxA1) and lipoxin A4, as well as the activating and proinflammatory protein serum amyloid A (PMID: 22610094).

Publikationen

SpeciesApplicationTitle
mouseWB,IHC,IF

Cell Death Dis

Amyloid-β(1-42) oligomer accelerates senescence in adult hippocampal neural stem/progenitor cells via formylpeptide receptor 2.

Authors - N He
humanWB

iScience

SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury.

Authors - Anteneh Getachew
humanWB,IHC

Oncol Rep

Formyl peptide receptor 2 expression predicts poor prognosis and promotes invasion and metastasis in epithelial ovarian cancer.

Authors - Xiaohui Xie
  • KD Validated
mouseWB

Hum Vaccin Immunother

Exogenous murine antimicrobial peptide CRAMP significantly exacerbates Ovalbumin-induced airway inflammation but ameliorates oxazolone-induced intestinal colitis in BALB/c mice.

Authors - Yang Li