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Adiponectin receptor Polyklonaler Antikörper

Adiponectin receptor Polyklonal Antikörper für IP, WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte und mehr (2)

Anwendung

WB, IP, IHC, IF, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14361-1-AP

Synonyme

ACDCR2, adiponectin receptor 2, Adiponectin receptor protein 2, ADIPOR1, ADIPOR2, PAQR2



Geprüfte Anwendungen

Erfolgreiche Detektion in WBHeLa-Zellen, A549-Zellen, humanes Plazenta-Gewebe, L02-Zellen, Rattenlebergewebe
Erfolgreiche IPMauslebergewebe

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:500-1:2000
Immunpräzipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

14361-1-AP bindet in WB, IP, IHC, IF, ELISA Adiponectin receptor und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
In Publikationen genannte Reaktivitäthuman, hamster, Hausschwein, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Adiponectin receptor fusion protein Ag5744
Vollständiger Name adiponectin receptor 2
Berechnetes Molekulargewicht 44 kDa
Beobachtetes Molekulargewicht 40-45 kDa
GenBank-ZugangsnummerBC051858
Gene symbol ADIPOR2
Gene ID (NCBI) 79602
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin (ADIPOR1 and ADIPOR2) have been identified. They mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. The human ADIPOR2 gene maps to chromosome 12p13.31, and encodes a 386-amino acid protein with a molecular weight of 44 kDa. This antibody raised against 1-147aa of human AdipoR2 may cross-react with AdipoR1.

Protokolle

Produktspezifische Protokolle
WB protocol for Adiponectin receptor antibody 14361-1-APProtokoll herunterladen
IP protocol for Adiponectin receptor antibody 14361-1-APProtokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
mouseIF

Redox Biol

Melatonin improves cardiac function in a mouse model of heart failure with preserved ejection fraction.

Authors - Yuan Liu
hamsterWB

Cancer Sci

Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.

Authors - Haoyi Jin
mouseWB

Food Funct

Quercetin regulates skeletal muscle fiber type switching via adiponectin signaling.

Authors - Xiaoling Chen
mouseWB

Food Funct

D-chiro-Inositol facilitates adiponectin biosynthesis and activates the AMPKα/PPARs pathway to inhibit high-fat diet-induced obesity and liver lipid deposition.

Authors - Qiong Yang
ratWB,IF

J Alzheimers Dis

Advanced Glycosylation End Products Induced Synaptic Deficits and Cognitive Decline Through ROS-JNK-p53/miR-34c/SYT1 Axis in Diabetic Encephalopathy

Authors - Rui Zhang
mouseWB

Gene

The Mef2c/AdipoR1 axis is responsible for myogenic differentiation and is regulated by resistin in skeletal muscles

Authors - Fengyun Wen