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Tested Applications
| Positive WB detected in | mouse brain tissue, rat brain tissue |
| Positive IHC detected in | mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 2 publications below |
Product Information
15325-1-AP targets MOAP1 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | MOAP1 fusion protein Ag2876 Predict reactive species |
| Full Name | modulator of apoptosis 1 |
| Calculated Molecular Weight | 39 kDa |
| Observed Molecular Weight | 36-39 kDa |
| GenBank Accession Number | BC015044 |
| Gene Symbol | MOAP1 |
| Gene ID (NCBI) | 64112 |
| RRID | AB_3085459 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q96BY2 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Modulator of apoptosis 1 (MOAP1, also known as MAP-1 and PNMA4) belongs to the PNMA family and is expressed in various types of tissues (PMID: 36724555). MAP1 contains a central BH3-like motif and interacts with the BAX protein (PMID: 11060313). It plays a central role in mitochondria and death receptor-mediated apoptosis and is associated with many diseases such as cancers and neurological diseases (PMID: 35269511).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for MOAP1 antibody 15325-1-AP | Download protocol |
| IHC protocol for MOAP1 antibody 15325-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Res Sq The Retrotransposon-Derived Capsid Genes PNMA1 and PNMA4 Maintain Reproductive Capacity | ||
bioRxiv The retrotransposon - derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity
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