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  • Featured Product
  • KD/KO Validated

FAH Polyclonal antibody

FAH Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 14928-1-AP

Synonyms

Beta diketonase, FAA, FAH, Fumarylacetoacetase, Fumarylacetoacetate hydrolase

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using FAH Polyclonal antibody (14928-1-AP)

    WB analysis using 14928-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 14928-1-AP (FAH antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

Tested Applications

Positive WB detected inmouse liver tissue, rat liver tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14928-1-AP targets FAH in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FAH fusion protein Ag6704
Full Name fumarylacetoacetate hydrolase (fumarylacetoacetase)
Calculated Molecular Weight 46 kDa
Observed Molecular Weight 40-45 kDa
GenBank Accession NumberBC002527
Gene Symbol FAH
Gene ID (NCBI) 2184
RRIDAB_2246738
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FAH is also named as FAA(fumarylacetoacetase), the last enzyme in tyrosine degradation, functionally important in the liver and kidney(PMID:8473520). FAH is a metabolic enzyme catalyzing the last step of tyrosine and phenylalanine catabolism: the hydrolysis of fumarylacetoacetate into acetoacetate and fumarate. In humans, deficiency of this activity is associated with the metabolic disease hereditary tyrosinaemia type I, which is also known as hepatorenal tyrosinaemia(PMID:17768357).

Protocols

Product Specific Protocols
WB protocol for FAH antibody 14928-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Int J Cancer

Protein predictive signatures for lymph node metastasis of gastric cancer.

Authors - Li Wei W
View Article

Am J Pathol

Protein Profiling of H. pylori-Associated Gastric Cancer.

Authors - Guodong Lian
View Article

PLoS One

Protein Profiling of Bladder Urothelial Cell Carcinoma.

Authors - Jinghai Hu
View Article

Int J Oncol

PMID: 29393385

Authors - Guodong Lian
View Article

Oncol Rep

The screening and analysis of protein signatures and signaling associated with chemoresistance based on Protein Pathway Array technology in gastric cancer.

Authors - Guodong Lian
View Article
humanWB

Cartilage

Low-Frequency Vibration Promotes Tumor Necrosis Factor-α Production to Increase Cartilage Degeneration in Knee Osteoarthritis.

Authors - Peng-Ming Yu
  • KD Validated
View Article