Published Applications
WB | See 3 publications below |
IHC | See 5 publications below |
IF | See 1 publications below |
FC | See 1 publications below |
Product Information
51024-1-AP targets CXCR7 in WB, IF, FC, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Cited Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Peptide Predict reactive species |
Full Name | chemokine (C-X-C motif) receptor 7 |
Calculated Molecular Weight | 362 aa, 41 kDa |
Observed Molecular Weight | 50 kDa |
GenBank Accession Number | BC036661 |
Gene Symbol | CXCR7 |
Gene ID (NCBI) | 57007 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P25106 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
CXCR7, also named as CMKOR1, GPR159 and RDC1, belongs to the G-protein coupled receptor 1 family. It is a receptor for CXCL12/SDF1. CXCR7 acts as coreceptor with CXCR4 for a restricted number of HIV isolates. CXCR7 was shown to contribute to neoangiogenesis in prostate cancer and to promote tumor cell proliferation in breast cancer and adenocarcinoma of the lung.
Publications
Species | Application | Title |
---|---|---|
Biomaterials The effect of stromal cell-derived factor-1α/heparin coating of biodegradable vascular grafts on the recruitment of both endothelial and smooth muscle progenitor cells for accelerated regeneration. | ||
Mod Pathol Strong expression of CXCL12 is associated with a favorable outcome in osteosarcoma. | ||
J Biol Chem Molecular mechanisms for enhancement of stromal cell-derived factor 1-induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1). | ||
PLoS One Expression of the Chemokine Receptor CXCR7 in CXCR4-Expressing Human 143B Osteosarcoma Cells Enhances Lung Metastasis of Intratibial Xenografts in SCID Mice. | ||
Scand J Gastroenterol CXCR7 as a chemokine receptor for SDF-1 promotes gastric cancer progression via MAPK pathways. |