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IL4R Monoclonal antibody, PBS Only (Capture/Detector)

IL4R Monoclonal Antibody for Cytometric bead array, Indirect ELISA

Host / Isotype

Mouse / IgM

Reactivity

human

Applications

Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3F12E8

Cat no : 67051-3-PBS

Synonyms

IL 4R subunit alpha, IL 4R alpha, IL 4 receptor subunit alpha, IL 4 binding protein, CD124

Validation Data Gallery

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  • Cytometric bead array standard curve of MP50242-1

    Cytometric bead array standard curve of MP50242-1

    Cytometric bead array standard curve of MP50242-1, IL4R Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67051-3-PBS. Detection antibody: 67051-2-PBS. Standard:Ag28411. Range: 1.563-100 ng/mL.

  • Cytometric bead array standard curve of MP50242-2

    Cytometric bead array standard curve of MP50242-2

    Cytometric bead array standard curve of MP50242-2, IL4R Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67051-4-PBS. Detection antibody: 67051-3-PBS. Standard:Ag28411. Range: 0.781-100 ng/mL.

  • Cytometric bead array standard curve of MP50242-3

    Cytometric bead array standard curve of MP50242-3

    Cytometric bead array standard curve of MP50242-3, IL4R Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67051-3-PBS. Detection antibody: 67051-5-PBS. Standard:Ag28411. Range: 0.195-100 ng/mL.

Product Information

67051-3-PBS targets IL4R as part of a matched antibody pair:

MP50242-1: 67051-3-PBS capture and 67051-2-PBS detection (validated in Cytometric bead array)

MP50242-2: 67051-4-PBS capture and 67051-3-PBS detection (validated in Cytometric bead array)

MP50242-3: 67051-3-PBS capture and 67051-5-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity human
Host / Isotype Mouse / IgM
Class Monoclonal
Type Antibody
Immunogen IL4R fusion protein Ag28411
Full Name interleukin 4 receptor
Calculated Molecular Weight 90 kDa
GenBank Accession NumberNM_000418
Gene Symbol IL-4R
Gene ID (NCBI) 3566
Conjugate Unconjugated
Form Liquid
Purification MethodEuglobulin precipitation
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

IL-4 receptor alpha chain (IL-4RA), also known as CD124, is a transmembrane glycoprotein expressed on a wide variety of hematopoietic and non-hematopoietic cells. It is a receptor for both IL-4 and IL-13. IL-4RA can complex with the common gamma chain (IL-2R gamma or CD132) and utilizes JAK1 and JAK2 for signal transduction, while complexes of IL-4RA with IL-13RA1 subunit mediate signals via JAK2 and Tyk2. The IL-4 response is involved in promoting Th2 differentiation. The IL-4/IL-13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation.