- HEK293 expressed
- Endotoxin-free
- Animal-component free
HumanKine® recombinant human SCF protein
Cat no : HZ-1024
Synonyms
c Kit ligand, DKFZp686F2250, KIT ligand, Kitl, KITLG, KL 1, Mast cell growth factor, MGF, SCF, SF, SHEP7, Stem cell factor
Validation Data Gallery
Technical Specifications
GeneID | 4254 |
Species | Human |
Expression | HEK293 |
Activity | 15-85 ng/mL EC50 |
Purity | >95% |
Endotoxin | <1 EU/µg |
Accession Number | P21583 |
Molecular Mass | 35 to 45 kDa, monomer, glycosylated |
Formulation | 1x PBS, See Certificate of Analysis for details |
Species Reactivity | human |
Stability and Reconstitution
Stability and Storage | Product Form | Temperature Conditions | Storage Time (From Date of Receipt) |
---|---|---|---|
Lyophilized | -20°C to -80°C | Until Expiry Date | |
Lyophilized | Room Temperature | 2 weeks | |
Reconstituted as per CofA | -20°C to -80°C | 6 months | |
Reconstituted as per CofA | 4°C | 1 week | |
Avoid repeated freeze-thaw cycles. |
Reconstitution | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA). |
Background
SCF is a hematopoietic growth factor that works by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation, and differentiation of hematopoietic cells (PMID: 12773427)
Synonyms
c Kit ligand, DKFZp686F2250, KIT ligand, Kitl, KITLG, KL 1, Mast cell growth factor, MGF, SCF, SF, SHEP7, Stem cell factor
Publications
Species | Title |
---|---|
Haematologica CD123 expression patterns and selective targeting with a CD123-specific antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia. | |
ACS Biomater Sci Eng Bioprinting of Human Cord Blood-Derived CD34+ Cells and Exploration of the Multilineage Differentiation Ability in Vitro. | |
Blood Res Generation of hematopoietic stem cells from human embryonic stem cells using a defined, stepwise, serum-free, and serum replacement-free monolayer culture method. | |
PLoS One A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors. | |
Sci Rep A 3D engineered scaffold for hematopoietic progenitor/stem cell co-culture in vitro. | |
iScience Use of dual-electron probes reveals the role of ferritin as an iron depot in ex vivo erythropoiesis. |