• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human BMP-4 protein


1.5-9 ng/mL EC50

Species Reactivity

human,mouse,bovine,Ciona intestinalis,rat



Cat no : HZ-1045


BMP 2B, BMP 4, BMP2B, BMP2B1, BMP4, BMP-4, Bone morphogenetic protein 2B, bone morphogenetic protein 4, DVR4, MCOPS6, ZYME

Technical Specifications

GeneID 652
Species Human
Expression HEK293
Activity(Primary) 1.5-9 ng/mL EC50
Purity >95%
Endotoxin<1 EU/µg
Accession NumberP12644
Molecular Mass 20 to 24 kDa reduced, 32 to 38 kDa non-reduced, homodimer, glycosylated
Formulation 2x PBS + 6% Ethanol, See Certificate of Analysis for details
Species Reactivity human,mouse,bovine,Ciona intestinalis,rat

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin (HSA).


Bone morphogenetic protein-4 (BMP4), also known as BMP2B and DVR4, belongs to the TGF-beta family. BMPs have been shown to promote astroglial differentiation both in vitro and in vivo. BMP4 can also induce cartilage and bone formation (PMID 16234975). Xeno-free Recombinant Human BMP-4 is expressed in human 293 cells as a disulfide linked homodimeric glycoprotein with an apparent molecular mass of 34 kDa. 


BMP 2B, BMP 4, BMP2B, BMP2B1, BMP4, BMP-4, Bone morphogenetic protein 2B, bone morphogenetic protein 4, DVR4, MCOPS6, ZYME




Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures.

Authors - Ronghui Li

Nat Methods

Long-term expansion of alveolar stem cells derived from human iPS cells in organoids.

Authors - YukiYamamoto


The RNA-binding protein RBPMS2 regulates development of gastrointestinal smooth muscle.

Authors - CécileNotarnicola

Cell Res

Visualization of aging-associated chromatin alterations with an engineered TALE system.

Authors - Ruotong Ren


Expression of BMPRIA on human thymic NK cell precursors: role of BMP signaling in intrathymic NK cell development.

Authors - LauraHidalgo

Nat Commun

Genetic pathways for differentiation of the peripheral nervous system in ascidians.

Authors - KanaWaki


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Angeles (Verified Customer) (02-09-2023)

It works fine

  • Applications: Cell culture
  • Cell Tissue Type: Lymphocytes, Dendritic cells, Macrophages