• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human TPO (Thrombopoietin) protein- GMP grade


100-500 ng/mL EC50 in MO7e cells in defined media

Specific Activity

>1.00 x 106 IU/mg

Species Reactivity




ISO 13485 certified HumanKine® human cell-expressed cytokines and growth factors

Cat no : HZ-1248-GMP


MGDF, MKCSF, ML, MPLLG, THPO, Thrombopoietin

Technical Specifications

GeneID 7066
Species Human
Expression HEK293
EC50 100-500 ng/mL EC50 in MO7e cells in defined media
Specific Activity>1.00 x 106 IU/mg
Purity >95%
Endotoxin<0.1 EU/μg
Accession NumberP40225
Molecular Mass 70 to 93 kDa reduced and non-reduced, monomer, glycosylated.
Formulation 1x PBS, See Certificate of Analysis for details
Species Reactivity human

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS containing pH 7.4 0.1% endotoxin-free recombinant human serum albumin (HSA).

GMP Quality Policies

HumanKine® GMP (Good Manufacturing Practice) recombinant proteins are manufactured and validated in accordance with ISO 13485 quality management system and is compliant with GMP.
Our GMP recombinant proteins are animal component free (ACF), xeno free (XF) and tag free (TF). Read more about these policies here.


TPO (Thrombopoietin) is a primary regulator of megakaryocyte development and platelet production in mammals. Human Thrombopoietin constitutively circulates and maintains thrombopoiesis through interaction with its cognate receptor, myeloproliferative leukemia protein(MPL). Thrombopoietin also plays an important role in the maintenance and regulation of hematopoietic stem cells (HSCs).


MGDF, MKCSF, ML, MPLLG, THPO, Thrombopoietin