Autophagy and Cell Death

Autophagy and cell death are fundamental cellular processes that play critical roles in the physiology and pathology of multicellular organisms.

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Autophagy is a conserved housekeeping process utilized by cells to maintain homeostasis by conveying intracellular components to lysosomal compartments for degradation and recycling.

Cell death can either be regulated, proceeding through precise signaling pathways or accidental resulting from unexpected cellular injury. While apoptosis is the earliest discovered regulated cell death pathway, several non-apoptotic regulated cell death pathways including pyroptosis, ferroptosis and necroptosis have gained prominence more recently.

Learn more about autophagy, apoptotic cell death, and non-apoptotic cell death pathways and discover how Proteintech products can accelerate your autophagy and cell death research.

Autophagy

Apoptotic Cell Death

Non-Apoptotic Cell Death

Related Posters

Recent Publications

Arthritis Rheumatol.

Contribution of Necroptosis to Myofiber Death in Idiopathic Inflammatory Myopathies

Front Immunol.

A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma

Int Immunopharmacol.

Isolongifolene alleviates liver ischemia/reperfusion injury by regulating AMPK-PGC1α signaling pathway-mediated inflammation, apoptosis, and oxidative stress

Autophagy

SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes

Antioxidants (Basel)

Quercetin Ameliorates Renal Injury and Pyroptosis in Lupus Nephritis through Inhibiting IL-33/ST2 Pathway In Vitro and In Vivo

Free Radic Biol Med.

Taurine attenuates neuronal ferroptosis by regulating GABAB/AKT/GSK3β/β-catenin pathway after subarachnoid hemorrhage

Nat Commun.

BNC1 deficiency-triggered ferroptosis through the NF2-YAP pathway induces primary ovarian insufficiency

Liver Int.

Apolipoprotein A-1 protected hepatic ischemia-reperfusion injury through suppressing macrophages pyroptosis via TLR4- NF-κB pathway

Cell Rep.

Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival

Nat Commun.

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy

Eur J Pharmacol.

Malvidin protects against lipopolysaccharide-induced acute liver injury in mice via regulating Nrf2 and NLRP3 pathways and suppressing apoptosis and autophagy

Redox Biol.

MPST deficiency promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via AKT