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VLDLR Polyclonal antibody

VLDLR Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (2)

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 19493-1-AP

Synonyms

CHRMQ1, VLDL R, VLDL receptor, VLDLR, VLDLRCH



Tested Applications

Positive WB detected inMCF-7 cells, mouse ovary tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

19493-1-AP targets VLDLR in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat, chicken, zebrafish
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name very low density lipoprotein receptor
Calculated Molecular Weight 96 kDa
Observed Molecular Weight 96 kDa, 160 kDa
GenBank Accession NumberNM_003383
Gene Symbol VLDLR
Gene ID (NCBI) 7436
RRIDAB_10644342
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

VLDLR binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. VLDLR binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (cytoplasmic domain of low-density lipoprotein receptor). For glycosylated, the MW of VLDLR migrates to ~160kd.

Protocols

Product Specific Protocols
WB protocol for VLDLR antibody 19493-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
zebrafishWB

Neuron

Molecular microcircuitry underlies functional specification in a basal ganglia circuit dedicated to vocal learning.

Authors - Hilliard Austin T AT
mouseWB

Food Funct

Monounsaturated fatty acid-enriched olive oil exacerbates chronic alcohol-induced hepatic steatosis and liver injury in C57BL/6J mice

Authors - Rui Guo
ratWB

Front Pharmacol

Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats.

Authors - Xue Wu
mouseWB

PLoS One

Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency.

Authors - Limin Liu
mouseWB

Front Nutr

Dietary camellia seed oil attenuates liver injury in mice chronically exposed to alcohol

Authors - Rui Guo
humanWB,IF

Front Oncol

VLDLR disturbs quiescence of breast cancer stem cells in a ligand-independent function

Authors - Mengying Yang
  • KD Validated