UQCRC1 Monoclonal antibody

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  WB analysis using 67888-1-Ig

  Various lysates were subjected to SDS PAGE followed by western blot with 67888-1-Ig (UQCRC1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

UQCRC1 Monoclonal Antibody for WB, ELISA

Cat No. 67888-1-Ig

Clone No.2G1C11

Publications(1)

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, pig and More (1)

Applications

WB, ELISA

Synonyms

Complex III subunit 1, Core protein I, D3S3191, QCR1, UQCR1, UQCRC1

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Tested Applications

• Positive WB detected in: LNCaP cells, Hela cells, K-562 cells, Jurkat cells, pig brain tissue, mouse brain tissue, rat brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below

Product Information

67888-1-Ig targets UQCRC1 in WB, ELISA applications and shows reactivity with Human, mouse, rat, pig samples.

• Tested Reactivity: Human, mouse, rat, pig
• Cited Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: UQCRC1 fusion protein Ag17506
• Full Name: ubiquinol-cytochrome c reductase core protein I
• Calculated Molecular Weight: 480 aa, 53 kDa
• Observed Molecular Weight: 45 kDa
• GenBank Accession Number: BC009586
• Gene Symbol: UQCRC1
• Gene ID (NCBI): 7384
• RRID: AB_2918644
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P31930
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

UQCRC1(Cytochrome b-c1 complex subunit 1, mitochondrial), also named as QCR1 and UQCR1, is a ubunit of the cytochrome bc1 complex (complex III) of the mitochondrial respiratory chain, may mediate the formation of the complex between cytochromes c and c1. The gene encodes a 53 kDa protein with a 34 amino acids transit peptide. It is associated with apoptosis or inhibition of cancer cell growth.

Publications

Species	Application	Title
human	WB	Bioorg Chem; SAR-guided development of indole-matrine hybrids as potential anticancer agents via mitochondrial stress/cytochrome c/caspase 3 signaling pathway; Authors - Lingyu Li