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UGT3A1 Polyclonal antibody, PBS Only

UGT3A1 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17268-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using UGT3A1 Polyclonal antibody (17268-1-AP)

    WB analysis using 17268-1-AP (same clone as 17268-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17268-1-AP (UGT3A1 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17268-1-PBS in a different storage buffer formulation.

Product Information

17268-1-PBS targets UGT3A1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen UGT3A1 fusion protein Ag11020
Full Name UDP glycosyltransferase 3 family, polypeptide A1
Calculated Molecular Weight 59 kDa
GenBank Accession NumberBC035012
Gene Symbol UGT3A1
Gene ID (NCBI) 133688
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

UGT3A1 (UDP Glycosyltransferase Family 3 Member A1) belongs to UDP-Glucuronosyltransferases (UGTs) superfamily. UGTs are membrane-bound enzymes localized at the subcellular level in the endoplasmic reticulum (ER) with an active site facing the lumenal side of the ER membrane. The genetic variation in UGT enzymes can modulate its regulation and expression, influencing UGT activity and resulting in pharmacological and physiologic effects. UGT3 family enzymes (UGT3A1 and UGT3A2) are expressed in the thymus, testis, and kidney, with a potential role in the metabolism of ursodeoxycholic acid during the treatment of cholestasis or gallstones.