TTL Recombinant antibody, PBS Only
TTL Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human, mouse, rat
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3P9
Cat no : 82763-5-PBS
Synonyms
Validation Data Gallery
Product Information
82763-5-PBS targets TTL in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | TTL fusion protein Ag4526 |
Full Name | tubulin tyrosine ligase |
Calculated Molecular Weight | 377 aa, 43 kDa |
Observed Molecular Weight | 43 kDa |
GenBank Accession Number | BC036819 |
Gene Symbol | TTL |
Gene ID (NCBI) | 150465 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Tubulin-tyrosine ligase (TTL) is the enzyme responsible for the reversible addition of a tyrosine residue at the carboxyl end of alpha-tubulin. TTL forms stable complexes with tubulin and inhibit tubulin polymerization. TTL is frequently suppressed during tumor progression with resulting accumulation of detyrosinated alpha-tubulin in tumor cells. TTL suppression in human cancers is associated with increased tumor aggressiveness.