TRAPPC5 Polyclonal antibody

TRAPPC5 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 20752-1-AP

Synonyms

TRAPPC 5, Trafficking protein particle complex subunit 5

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Validation Data Gallery

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  WB analysis using 20752-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 20752-1-AP (TRAPPC5 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HEK-293 cells, HepG2 cells, PC-3 cells

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:8000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

20752-1-AP targets TRAPPC5 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: TRAPPC5 fusion protein Ag13185
• Full Name: trafficking protein particle complex 5
• Calculated Molecular Weight: 188 aa, 21 kDa
• Observed Molecular Weight: 21-23 kDa
• GenBank Accession Number: BC042161
• Gene Symbol: TRAPPC5
• Gene ID (NCBI): 126003
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Transport protein particle (TRAPP, also known as trafficking protein particle), a multimeric guanine nucleotide-exchange factor, regulates multiple membrane trafficking pathways (PMID: 20966969). TRAPPC5 is a component of the TRAPP complexes and is involved in processes such as intracellular vesicle transport. In hepatocellular carcinoma, upregulated expression of TRAPPC5 can enhance cancer cell proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) and promote tumorigenesis (PMID: 35425722).