TMEM59 Polyclonal antibody

TMEM59 Polyclonal Antibody for WB, IF, IHC, ELISA

Host / Isotype

Rabbit / IgG







Cat no : 24134-1-AP


C1orf8, HSPC001, Liver membrane bound protein, TMEM59, transmembrane protein 59, UNQ169/PRO195

Tested Applications

Positive WB detected inMCF-7 cells
Positive IHC detected inhuman breast cancer tissue, human liver tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHepG2 cells

Recommended dilution

Western Blot (WB)WB : 1:200-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:10-1:100
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 2 publications below

Product Information

24134-1-AP targets TMEM59 in WB, IF, IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TMEM59 fusion protein Ag21150
Full Name transmembrane protein 59
Calculated Molecular Weight 36 kDa
Observed Molecular Weight 41 kDa
GenBank Accession NumberBC016374
Gene Symbol TMEM59
Gene ID (NCBI) 9528
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TMEM59 is a regulator of autophagy in response to bacterial infection. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing of TMEM59 results in multiple transcript variants.


Product Specific Protocols
WB protocol for TMEM59 antibody 24134-1-APDownload protocol
IHC protocol for TMEM59 antibody 24134-1-APDownload protocol
IF protocol for TMEM59 antibody 24134-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Mol Cell

An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress.

Authors - Julian Nüchel

J Extracell Vesicles

A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells.

Authors - Charles P Hinzman