Validation Data Gallery
|Positive WB detected in||mouse liver tissue, human brain tissue, human heart tissue, human liver tissue, mouse heart tissue, mouse kidney tissue, mouse placenta tissue, rat liver tissue|
|Positive IP detected in||mouse liver tissue|
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB|
|Sample-dependent, check data in validation data gallery|
13838-1-AP targets TCF4/TCF7L2 in WB, IP, IHC, IF, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||TCF4/TCF7L2 fusion protein Ag4786|
|Full Name||transcription factor 7-like 2 (T-cell specific, HMG-box)|
|Calculated molecular weight||619 aa, 68 kDa|
|Observed molecular weight||68 kDa|
|GenBank accession number||BC032656|
|Gene ID (NCBI)||6934|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Cell Mol Immunol
TRIM27 maintains gut homeostasis by promoting intestinal stem cell self-renewal
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
Front Cell Dev Biol
Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells in vitro by Forming a Complex With Tcf4 and β-Catenin.
Mol Cancer Res
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
J Biol Chem
HBP1-mediated regulation of p21 through Mdm2/p53 and TCF4/EZH2 pathways and its impact on cell senescence and tumorigenesis.