SMOC2 Polyclonal antibody

SMOC2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 31063-1-AP

Synonyms

bA270C4A.1, bA37D8.1, dJ421D16.1, MST117, MSTP117, MSTP140, SMAP 2, SMAP2, SMOC 2, SMOC2

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Validation Data Gallery

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  WB analysis using 31063-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31063-1-AP (SMOC2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HCT 116 cells, mouse brain tissue, mouse ovary tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

31063-1-AP targets SMOC2 in WB, ELISA applications and shows reactivity with Human, mouse samples.

• Tested Reactivity: Human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SMOC2 fusion protein Ag34966
• Full Name: SPARC related modular calcium binding 2
• Calculated Molecular Weight: 50 kDa
• Observed Molecular Weight: 49-50 kDa
• GenBank Accession Number: BC047583
• Gene Symbol: SMOC2
• Gene ID (NCBI): 64094
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Secreted modular calcium-binding protein 2 (SMOC2), which is a member of the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins, interacts with matrix proteins, cell surface receptors, cytokines, proteasomes and other effector molecules to regulate cell-cell and cell-microenvironment communication (PMID: 36513634). It is expected to be located in extracellular space. The calculated molecular weight of SMOC2 is 50 kDa. In recent years, SMOC2 has been reported to be highly expressed in tumor tissues and to promote tumor migration, invasion and growth. In addition to its role in tumor progression, it also regulates wound healing, bone growth, fibrosis and embryogenesis (PMID: 36513634).