CoraLite® Plus 488-conjugated SAMD9L Polyclonal antibody

• Featured Product
• KD/KO Validated

SAMD9L Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-25173

Synonyms

C7orf6, DRIF2, FLJ39885, KIAA2005, SAMD9L, UEF, UEF1

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Validation Data Gallery

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  IF Staining of 3T3-L1 using CL488-25173

  Immunofluorescent analysis of (-20°C Ethanol) fixed 3T3-L1 cells using CoraLite® Plus 488 SAMD9L antibody (CL488-25173) at dilution of 1:200.

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Tested Applications

• Positive IF/ICC detected in: 3T3-L1 cells

Recommended dilution

• Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

CL488-25173 targets SAMD9L in IF/ICC applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SAMD9L fusion protein Ag18541
• Full Name: sterile alpha motif domain containing 9-like
• Calculated Molecular Weight: 1584 aa, 185 kDa
• Observed Molecular Weight: 160-180 kDa
• GenBank Accession Number: BC127118
• Gene Symbol: SAMD9L
• Gene ID (NCBI): 219285
• Conjugate: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 493 nm / 522 nm
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
• Storage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Background Information

Sterile alpha motif domain-containing protein 9-like(SAMD9L), also named as C7orf6, DRIF2, KIAA2005 and UEF, is a cytoplasmic protein that acts as a tumor suppressor but also plays a key role in cell proliferation and the innate immune response to viral infection. SAMD9L protein is an endosome fusion facilitator which causes myeloid malignancies in mice similar to human diseases with monosomy 7. The SAMD9L protein also appears to play an important role in the brain, particularly the part of the brain that coordinates movement (the cerebellum). SAMD9L has two isoforms with MW 185 kDa and 47 kDa.