S1PR3 Recombinant antibody

S1PR3 Uni-rAb^TM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

241905C2

Cat no : 84697-1-RR

Synonyms

Endothelial differentiation G-protein coupled receptor 3, EDG3, EDG 3, C9orf47, C9orf108

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Validation Data Gallery

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  WB analysis using 84697-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84697-1-RR (S1PR3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: Jurkat cells, HepG2 cells, MCF-7 cells, HEK-293 cells, HeLa cells

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

84697-1-RR targets S1PR3 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Peptide
• Full Name: sphingosine-1-phosphate receptor 3
• Calculated Molecular Weight: 42 kDa
• Observed Molecular Weight: 39 kDa
• GenBank Accession Number: NM_005226
• Gene Symbol: S1PR3
• Gene ID (NCBI): 1903
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

S1PR3 (sphingosine-1-phosphate receptor 3), also known as as S1P3 or EDG3, is one of five G-protein-coupled receptors for sphingosine-1-phosphate (S1P). S1P1 and its receptors have important regulatory functions in normal physiology and disease processes, particularly involving the immune, central nervous, and cardiovascular systems (PMID: 21339489). S1PR3 has a role in the development of a stable and mature vascular system during embryonic development (PMID: 15138255).