RBMXL2 Polyclonal antibody

RBMXL2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 27987-1-AP

Synonyms

HNRPGT, HNRNPGT, HNRNPG T, hnRNP G T

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Validation Data Gallery

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  WB analysis using 27987-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 27987-1-AP (RBMXL2 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: mouse testis tissue, rat testis tissue

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:16000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

27987-1-AP targets RBMXL2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: RBMXL2 fusion protein Ag27624
• Full Name: RNA binding motif protein, X-linked-like 2
• Calculated Molecular Weight: 43 kDa
• Observed Molecular Weight: 43 kDa
• GenBank Accession Number: BC057796
• Gene Symbol: RBMXL2
• Gene ID (NCBI): 27288
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

RBMXL2 (RNA-binding motif protein, X-linked-like-2), also known as heterogeneous nuclear ribonucleoproteins G-testis or hnRNP-GT, is a testis-specific nuclear RNA binding protein that plays a crucial role in male meiosis (PMID: 34927545). The protein is part of an anciently diverged family of RNA-binding proteins and shares significant homology with RBMX, another RNA-binding protein that is important for controlling splicing, transcription, and genome stability (PMID: 39356106). The expression of RBMXL2 is restricted to the testis, and it is highly expressed during the pachytene and diplotene stages of meiosis, which are characterized by high levels of transcription and alternative splicing (PMID: 34927545).