PPRC1 Polyclonal antibody

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• PPRC1 Polyclonal antibody (25429-1-AP)

PPRC1 Polyclonal Antibody for WB, ELISA

Cat No. 25429-1-AP Copied!

Publications (2)

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

KIAA0595, PGC 1 related coactivator, PPRC1, PRC, RP11 302K17.6

• 

  WB analysis of NIH/3T3 using 25429-1-AP

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 25429-1-AP (PPRC1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis using 25429-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 25429-1-AP (PPRC1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: NIH/3T3 cells, C6 cells

Recommended dilution

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

25429-1-AP targets PPRC1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag11940

  Product name: Recombinant human PPRC1 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1193-1542 aa of BC063806

  Sequence: VIPEVGSRWNVKRHQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRRGRNSRSVSSGSNRTSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRSPSPRRRSDRRRRSYRSHDHYQRQRVLQKERAIEERRVVFIGKIPGRMTRSELKQRFSVFGEIEECTIHFRVQGDNYGFVTYRYAEEAFAAIESGHKLRQADEQPFDLCFGGRRQFCKRSYSDLDSNREDFDPAPVKSKFDSLDFDTLLKQAQKNLRR

• Full Name: peroxisome proliferator-activated receptor gamma, coactivator-related 1
• Calculated Molecular Weight: 1542 aa, 165 kDa
• Observed Molecular Weight: 177 kDa
• GenBank Accession Number: BC063806
• Gene Symbol: PPRC1
• Gene ID (NCBI): 23082
• RRID: AB_2880074
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q5VV67
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Peroxisome proliferator-activated receptor gamma, co-activator-related 1 (Pprc1) is the third member of the Pgc1 family, which contributes to mitochondrial biogenesis and orchestrates response to metabolic stress by promoting the expression of multiple genes specifying inflammation, proliferation, and metabolic reprogramming.

Publications

What published studies show

The PPRC1 Polyclonal antibody (Cat# 25429-1-AP) has 2 total citations. These publications appear in Cancer Research and Scientific Reports. The cited research focuses on mitochondrial biogenesis in cancer contexts—specifically, PGC-1α degradation and radiation resistance in glioma, and CRIP1-mediated inhibition of cutaneous melanoma progression through TFAM-dependent mitochondrial biogenesis. Both studies utilized the antibody for Western blot analysis in human samples.

Automatically generated from the 2 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	Cancer Res; PGC-1α degradation suppresses mitochondrial biogenesis to confer radiation resistance in glioma; Authors - Mengjie Zhao
human	WB	Sci Rep; CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis; Authors - Jianqiang Wu