PFKFB3 Monoclonal antibody
PFKFB3 Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse
Applications
ELISA
Conjugate
Unconjugated
CloneNo.
4D1B11
Cat no : 60241-1-Ig
Synonyms
Validation Data Gallery
Product Information
The immunogen of 60241-1-Ig is PFKFB3 Fusion Protein expressed in E. coli.
| Tested Reactivity | human, mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | PFKFB3 fusion protein Ag4737 |
| Full Name | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| Calculated Molecular Weight | 520 aa, 60 kDa |
| Observed Molecular Weight | 55-58 kDa |
| GenBank Accession Number | BC040482 |
| Gene Symbol | PFKFB3 |
| Gene ID (NCBI) | 5209 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
PFKFB3, also named as NY-REN-56 and iPFK-2, plays a role in glucose metabolism. It synthesis and degradation of fructose 2,6-bisphosphate. Endogenously generated adenosine cooperates with bacterial components to increase PFKFB3 isozyme activity, resulting in greater fructose 2,6-bisphosphate accumulation. PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 and STAT5.
