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PDZD8 Polyclonal antibody, PBS Only

PDZD8 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 25512-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using PDZD8 Polyclonal antibody (25512-1-AP)

    WB analysis using 25512-1-AP (same clone as 25512-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25512-1-AP (PDZD8 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25512-1-PBS in a different storage buffer formulation.

Product Information

25512-1-PBS targets PDZD8 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PDZD8 fusion protein Ag21914
Full Name PDZ domain containing 8
Calculated Molecular Weight 1154 aa, 129 kDa
Observed Molecular Weight150-160 kDa
GenBank Accession NumberBC028375
Gene Symbol PDZD8
Gene ID (NCBI) 118987
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

PDZD8 (PDZ domain containing 8) is an SMP (synaptotagmin-like mitochondrial-lipid-binding) domain-containing protein belonging to the tubular lipid-binding protein (TULIP) superfamily of lipid transfer proteins (PMID: 37961523). PDZD8 is an integral ER transmembrane protein present at ER-mitochondria contacts (PMID: 29097544). It is involved in regulating ER-mitochondria associations, mitochondrial calcium ion homeostasis, and lipid transport between the ER and late endosomes/lysosomes (PMID: 37247681; 29097544; 33912962).