• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

P2RX6 Recombinant antibody, PBS Only

P2RX6 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241620B10

Cat no : 84458-4-PBS

Synonyms

P2XM, P2X6, P2X purinoceptor 6, P2RXL1, ATP receptor

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of mouse skeletal muscle tissue using P2RX6 Recombinant antibody (84458-4-RR)

    WB analysis of mouse skeletal muscle using 84458-4-RR (same clone as 84458-4-PBS)

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 84458-4-RR (P2RX6 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84458-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84458-4-RR

    Affinity and Kinetic Characterization of 84458-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84458-4-RR against Human P2RX6 were performed. The affinity constant is below 1 pM.

Product Information

The immunogen of 84458-4-PBS is P2RX6 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen P2RX6 fusion protein Ag12331
Full Name purinergic receptor P2X, ligand-gated ion channel, 6
Calculated Molecular Weight 431 aa, 48 kDa
Observed Molecular Weight 45 kDa
GenBank Accession NumberBC033488
Gene Symbol P2RX6
Gene ID (NCBI) 9127
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The P2 receptors have two subfamilies in mammalian cells, P2X and P2Y. P2X family of ligand-gated ion channel receptors have seven members, P2RX1-7, which all constitute non-selective cation channels proposed to be functional under a homo- or heterotrimeric association. P2RX6 is predominantly expressed in skeletal muscle, and regulated by p53. It's reported that ATP might increase renal cell carcinoma cells migration and invasion through P2RX6.(PMID: 31159832, PMID:9242461)