NMNAT2 Recombinant antibody, PBS Only

NMNAT2 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241484E10

Cat no : 84307-5-PBS

Synonyms

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2, NaMN adenylyltransferase 2, KIAA0479, EC:2.7.7.1, C1orf15

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Validation Data Gallery

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  WB analysis using 84307-5-RR (same clone as 84307-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84307-5-RR (NMNAT2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84307-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84307-5-RR

  Biolayer interferometry (BLl) kinetic assays of 84307-5-RR against Human NMNAT2 were performed. The affinity constant is below 1 pM.

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Product Information

The immunogen of 84307-5-PBS is NMNAT2 Fusion Protein expressed in E. coli.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: NMNAT2 fusion protein Ag26909
• Full Name: nicotinamide nucleotide adenylyltransferase 2
• Calculated Molecular Weight: 34 kDa
• Observed Molecular Weight: 32-34 kDa
• GenBank Accession Number: BC020998
• Gene Symbol: NMNAT2
• Gene ID (NCBI): 23057
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

NMNA2 (Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 ) is an axon survival factor required for the maintenance of healthy axons, it acts by delaying Wallerian axon degeneration which is an evolutionarily conserved process that drives the loss of damaged axons.