Anti-Human N-cadherin/CD325 Rabbit Recombinant Antibody, PBS Only

N-cadherin/CD325 Uni-rAb^TM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

230259D7

Cat no : 98006-1-PBS

Synonyms

N-cadherin, CDHN, CDH2, CD325, Cadherin-2

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Validation Data Gallery

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  FC experiment of HeLa using 98006-1-PBS

  1x10^6 HeLa cells were stained with 0.25 ug Anti-Human N-cadherin/CD325 (98006-1-PBS, Clone: 230259D7) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Control Antibody and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed.

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Tested Applications

• Positive FC detected in: HeLa cells

Recommended dilution

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

98006-1-PBS targets N-cadherin/CD325 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: cadherin 2, type 1, N-cadherin (neuronal)
• Calculated Molecular Weight: 100 kDa
• GenBank Accession Number: NM_001792.4
• Gene Symbol: N-cadherin
• Gene ID (NCBI): 1000
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS only
• Storage Conditions: Store at -80°C. Stable for one year after shipment.

Background Information

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin), also known as CDH2 (cadherin 2), is a 130-kDa transmembrane protein and a classical member of the cadherin superfamily which also include E-, P-, R-, and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons, endothelial cells and cardiac myocytes (PMID: 11282032; 9508779; 8125202). N-cadherin has functions in early brain morphogenesis, synaptogenesis and synaptic plasticity (PMID: 23321619).