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  • KD/KO Validated

MYO18A Polyclonal antibody

MYO18A Polyclonal Antibody for WB, IP, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 14611-1-AP


CD245, KIAA0216, MAJN, MYO18A, Myosin containing a PDZ domain, myosin XVIIIA, MYSPDZ, SPR210

Tested Applications

Positive WB detected inJurkat cells, HeLa cells, K-562 cells, Neuro-2a cells, NIH/3T3 cells
Positive IP detected inHeLa cells
Positive IHC detected inmouse heart tissue, mouse skeletal muscle tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:1000-1:6000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14611-1-AP targets MYO18A in WB, IP, IF, FC, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen MYO18A fusion protein Ag6185
Full Name myosin XVIIIA
Calculated Molecular Weight 233 kDa
Observed Molecular Weight 230 kDa, 190 kDa
GenBank Accession NumberBC039612
Gene Symbol MYO18A
Gene ID (NCBI) 399687
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

MYO18A is an unconventional myosin that may play a role in the stabilization and organization of the actin cytoskeleton. Recently MYO18A has been identified as the receptor of SP and is responsible for clearance of SP-A-opsonized bacteria in in vivo infection. Two different isoforms of mouse Myo18A have been identified: Myo18A-alpha and Myo18A-beta as 230- and 190-kDa proteins, respectively. Myo18a-alpha colocalizes with the ER-Golgi complex and with membrane ruffles and filopodia, while Myo18a-beta localizes diffusely to the cytoplasm.


Product Specific Protocols
WB protocol for MYO18A antibody 14611-1-APDownload protocol
IHC protocol for MYO18A antibody 14611-1-APDownload protocol
IP protocol for MYO18A antibody 14611-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



J Clin Invest

A pro-tumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma.

Authors - Xiaochao Tan
  • KD Validated

Cell Death Differ

The Smad4-MYO18A-PP1A complex regulates β-catenin phosphorylation and pemigatinib resistance by inhibiting PAK1 in cholangiocarcinoma.

Authors - Jialiang Liu
  • KD Validated

Cell Syst

A Portrait of the Human Organelle Proteome In Space and Time during Cytomegalovirus Infection.

Authors - Pierre M Jean Beltran
  • KD Validated


Identification of CD245 as myosin 18A, a receptor for surfactant A: A novel pathway for activating human NK lymphocytes.

Authors - A De Masson


Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role For Peroxiredoxin 4 in Proinsulin Folding.

Authors - Duc T Tran

J Cell Sci

Pushing myelination: developmental regulation of myosin expression drives oligodendrocyte morphological differentiation

Authors - Helena Sofia Domingues


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Sammy (Verified Customer) (04-22-2024)

Detects several bands. One at the correct MW that will need to be validated by KO/KD.

  • Applications: Western Blot
  • Primary Antibody Dilution: 1 : 1000
  • Cell Tissue Type: HUVEC