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  • Featured Product
  • KD/KO Validated

LUZP1 Polyclonal antibody, PBS Only

LUZP1 Polyclonal Antibody for WB, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17483-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using LUZP1 Polyclonal antibody (17483-1-AP)

    WB analysis using 17483-1-AP (same clone as 17483-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17483-1-AP (LUZP1 antibody) at dilution of 1:15000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17483-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse brain tissue using LUZP1 Polyclonal antibody (17483-1-AP)

    WB analysis of mouse brain using 17483-1-AP (same clone as 17483-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 17483-1-AP (LUZP1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17483-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of mouse brain tissue using LUZP1 Polyclonal antibody (17483-1-AP)

    IP experiment of mouse brain using 17483-1-AP (same clone as 17483-1-PBS)

    IP result of anti-LUZP1 (IP:17483-1-AP, 4ug; Detection:17483-1-AP 1:10000) with mouse brain tissue lysate 1680 ug. This data was developed using the same antibody clone with 17483-1-PBS in a different storage buffer formulation.

Product Information

17483-1-PBS targets LUZP1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen LUZP1 fusion protein Ag11518
Full Name leucine zipper protein 1
Calculated Molecular Weight 1026 aa, 115 kDa
Observed Molecular Weight 120 kDa
GenBank Accession NumberBC051733
Gene Symbol LUZP1
Gene ID (NCBI) 7798
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

LUZP1, also known as LUZP, is predominantly expressed in the brain, whereas it is present in the nucleus of neurons. LUZP1 is a centrosome, actin, and midbody-localizing protein implicated in ciliogenesis regulation and actin cytoskeleton stability (PMID: 33869174). LUZP1 null mice present defective neural tube closure and cardiovascular problems, which cause perinatal death. In addition, LUZP1 has also been implicated in the etiology of diseases like the 1p36 and the Townes-Brocks syndromes (PMID: 35738212).