LHFPL4 Polyclonal antibody

LHFPL4 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 21094-1-AP

Synonyms

Lipoma HMGIC fusion partner-like 4 protein, LHFPL tetraspan subfamily member 4 protein, GARLH4, GABAA receptor regulatory Lhfpl4

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Validation Data Gallery

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  WB analysis using 21094-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 21094-1-AP (LHFPL4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: mouse heart tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

21094-1-AP targets LHFPL4 in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: LHFPL4 fusion protein Ag15349
• Full Name: lipoma HMGIC fusion partner-like 4
• Calculated Molecular Weight: 247 aa, 27 kDa
• Observed Molecular Weight: 27 kDa
• GenBank Accession Number: BC113964
• Gene Symbol: LHFPL4
• Gene ID (NCBI): 375323
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen Affinity purified
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

LHFPL4, or Lipoma HMGIC Fusion Partner-Like 4, is a member of the tetraspanin superfamily of transmembrane proteins. LHFPL4 interacts tightly with GABAAR subunits and is selectively enriched at inhibitory synapses. It is important for GABAAR clustering both in vitro and in vivo, and it is required for surface clustering but not the trafficking of GABAARs (PMID: 28978485).