LAPTM4B Polyclonal antibody, PBS Only

• Featured Product
• KD/KO Validated

LAPTM4B Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 18895-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis of mouse lymph using 18895-1-AP (same clone as 18895-1-PBS)

  mouse lymph tissue were subjected to SDS PAGE followed by western blot with 18895-1-AP (LAPTM4B antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18895-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat lymph using 18895-1-AP (same clone as 18895-1-PBS)

  rat lymph tissue were subjected to SDS PAGE followed by western blot with 18895-1-AP (LAPTM4B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18895-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 18895-1-AP (same clone as 18895-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 18895-1-AP (LAPTM4B Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 18895-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 18895-1-AP (same clone as 18895-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 18895-1-AP (LAPTM4B Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18895-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 18895-1-AP (same clone as 18895-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 18895-1-AP (LAPTM4B Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18895-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 18895-1-AP (same clone as 18895-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 18895-1-AP (LAPTM4B Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 18895-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 18895-1-AP (same clone as 18895-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 18895-1-AP (LAPTM4B Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 18895-1-PBS in a different storage buffer formulation.

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Product Information

18895-1-PBS targets LAPTM4B in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: LAPTM4B fusion protein Ag13521
• Full Name: lysosomal protein transmembrane 4 beta
• Calculated Molecular Weight: 41 kDa
• Observed Molecular Weight: 24 kDa
• GenBank Accession Number: BC014129
• Gene Symbol: LAPTM4B
• Gene ID (NCBI): 55353
• RRID: AB_10597385
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

LAPTM4B, a novel oncoprotein, is associated with the prognosis of cancer, and may play important roles in the initiation, promotion and metastasis of tumors. It was initially identified as a hepatocellular carcinoma-associated gene, and was recently shown to be up-regulated in various human cancers. Some studies indicated that LAPTM4B may be an useful marker of prognosis in ovarian carcinoma and endometrial cancer. LAPTM4B belongs to the LAPTM4/LAPTM5 transporter family. It has 3 isoforms with molecular masses 41 kDa, 35 kDa and 24 kDa. This antibody can recognize all the 3 isoforms of LAPTM4B.