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  • Featured Product
  • KD/KO Validated

Integrin Alpha 4 Polyclonal antibody, PBS Only

Integrin Alpha 4 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 19676-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using Integrin Alpha 4 Polyclonal antibody (19676-1-AP)

    WB analysis using 19676-1-AP (same clone as 19676-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 19676-1-AP (Integrin alpha-4 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19676-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using Integrin Alpha 4 Polyclonal antibody (19676-1-AP)

    IHC staining of human tonsillitis using 19676-1-AP (same clone as 19676-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 19676-1-AP (Integrin alpha-4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 19676-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using Integrin Alpha 4 Polyclonal antibody (19676-1-AP)

    IHC staining of human tonsillitis using 19676-1-AP (same clone as 19676-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 19676-1-AP (Integrin alpha-4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 19676-1-PBS in a different storage buffer formulation.

Product Information

19676-1-PBS targets Integrin Alpha 4 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
Calculated Molecular Weight 115 kDa
Observed Molecular Weight 140-150 kDa
GenBank Accession NumberNM_000885
Gene Symbol Integrin alpha 4
Gene ID (NCBI) 3676
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ITGA4, also named as CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1 and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.