IL-1R2 Monoclonal antibody, PBS Only
IL-1R2 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human, mouse
Applications
WB, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3H4H4
Cat no : 60262-1-PBS
Synonyms
Validation Data Gallery
Product Information
60262-1-PBS targets IL-1R2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | IL-1R2 fusion protein Ag4495 |
Full Name | interleukin 1 receptor, type II |
Calculated Molecular Weight | 398 aa, 45 kDa |
Observed Molecular Weight | 45 kDa |
GenBank Accession Number | BC039031 |
Gene Symbol | IL1R2 |
Gene ID (NCBI) | 7850 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.