IHCeasy SHH Ready-To-Use IHC Kit
SHH Ready-to-use reagent kit for IHC.
Cat no : KHC0134
HHG 1, HHG1, HLP3, HPE3, MCOPCB5, SHH, SMMCI, Sonic hedgehog protein, TPT, TPTPS
KHC0134 is a ready-to-use IHC kit for staining of SHH. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
|IHCeasy SHH Ready-To-Use IHC Kit
|Primary antibody type
|Secondary antibody type
|Antigen Retrieval Buffer
|100 mL ×2
|Chromogen Component A
|Chromogen Component B
|Counter Staining Reagent
SHH, also named as HHG-1, belongs to the hedgehog family. SHH binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. It regulates another target, the gli oncogene. The Shh protein is synthesized as a 45-kDa precursor that undergoes an autocatalytic processing event that produces a 19-kDa N-terminal product, responsible for all signaling activities, and a 25-kDa C-terminal fragment. This kit could detect the N-terminal fragment and full length form.
|All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.
|HHG 1, HHG1, HLP3, HPE3, MCOPCB5, SHH, SMMCI, Sonic hedgehog protein, TPT, TPTPS