IHCeasy PML Ready-To-Use IHC Kit
PML Ready-to-use reagent kit for IHC.
Human, Mouse, Rat
Cat no : KHC1576
MYL, PML, PP8675, promyelocytic leukemia, RING finger protein 71, RNF71, TRIM19
KHC1576 is a ready-to-use IHC kit for staining of PML. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
|IHCeasy PML Ready-To-Use IHC Kit
|Primary antibody type
|Secondary antibody type
|Human, Mouse, Rat
|Antigen Retrieval Buffer
|100 mL ×2
|Chromogen Component A
|Chromogen Component B
|Counter Staining Reagent
PML, also named as MYL, RNF71 and TRIM19, is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. It functions as tumor suppressor. PML is required for normal, caspase-dependent apoptosis in response to DNA damage, FAS, TNF, or interferons. It plays a role in transcription regulation, DNA damage response, DNA repair and chromatin organization. PML plays a role in processes regulated by retinoic acid, regulation of cell division, terminal differentiation of myeloid precursor cells and differentiation of neural progenitor cells. It regulates PTEN compartmentalization through the inhibition of USP7-mediated deubiquitinylation.
|All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.
|MYL, PML, PP8675, promyelocytic leukemia, RING finger protein 71, RNF71, TRIM19