IHCeasy MGMT Ready-To-Use IHC Kit
MGMT Ready-to-use reagent kit for IHC.
Cat no : KHC0771
Homo sapiens (Human), MGMT
KHC0771 is a ready-to-use IHC kit for staining of MGMT. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
|IHCeasy MGMT Ready-To-Use IHC Kit
|Primary antibody type
|Secondary antibody type
|Antigen Retrieval Buffer
|100 mL ×2
|Chromogen Component A
|Chromogen Component B
|Counter Staining Reagent
MGMT is the primary vehicle for cellular removal of alkyl lesions from the O-6 position of guanine and the O-4 position of thymine. While key to the maintenance of genomic integrity, MGMT also removes damage induced by alkylating chemotherapies, inhibiting the efficacy of cancer treatment. MGMT is the primary mechanism for the removal of alkylation damage from the O-6 position of guanine. The O-6 position of guanine is one of several positions in DNA bases to which alkyl groups are attached in SN1 alkylation reactions, and this repair has been well-characterized in mammalian cells and via MGMT homologs in bacteria and Archaea.
|All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.
|Homo sapiens (Human), MGMT