IHCeasy DACH1 Ready-To-Use IHC Kit
DACH1 Ready-to-use reagent kit for IHC.
Human, Mouse, Rat
Cat no : KHC0055
DACH, DACH1, Dachshund homolog 1
KHC0055 is a ready-to-use IHC kit for staining of DACH1. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
|IHCeasy DACH1 Ready-To-Use IHC Kit
|Primary antibody type
|Secondary antibody type
|Human, Mouse, Rat
|Antigen Retrieval Buffer
|100 mL ×2
|Chromogen Component A
|Chromogen Component B
|Counter Staining Reagent
DACH1, a homologue of the Drosophila dachshund gene, is a key regulator of cell fate determination during eye, leg, and brain development in the fly. Through interacting with NCoR and Smad4, DACH1 is able to inhibit the transforming growth factor-beta (TGF-beta) signaling pathway. DACH1 can inhibit breast cancer cellular proliferation via cyclin D1, suggesting a possible role in tumor suppression. Additionally, DACH1 plays an important role in negative regulation of RANKL (Receptor activator of NF-kappaB ligand ) gene expression in marrow stromal/preosteoblast cells, and loss of DACH1 expression might be involved in endometrial cancer progression. It has also been reported that Dach1 regulates neural crest migration during Xenopus embryonic development.
|All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.
|DACH, DACH1, Dachshund homolog 1