IHCeasy CUL3 Ready-To-Use IHC Kit
CUL3 Ready-to-use reagent kit for IHC.
Cat no : KHC1066
CUL 3, CUL3, cullin 3, KIAA0617
KHC1066 is a ready-to-use IHC kit for staining of CUL3. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
|IHCeasy CUL3 Ready-To-Use IHC Kit
|Primary antibody type
|Secondary antibody type
|Antigen Retrieval Buffer
|100 mL ×2
|Chromogen Component A
|Chromogen Component B
|Counter Staining Reagent
Cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ligase are the largest family of ubiquitin ligases which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. One of seven cullin proteins serves as a scaffold protein for the assembly of the multisubunit ubiquitin ligase complex. CUL3 (Cullin-3) ubiquitin ligase complex targets multiple substrate for ubiquitination including cyclin E and of cyclin D1. Defects in CUL3 are the cause of Pseudohypoaldosteronism type 2E (PHA2E) characterized by severe hypertension, hyperkalemia, hyperchloremia, hyperchloremic metabolic acidosis, and correction of physiologic abnormalities by thiazide diuretics.
|All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.
|CUL 3, CUL3, cullin 3, KIAA0617