IGDCC3 Polyclonal antibody

IGDCC3 Polyclonal Antibody for IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IP, ELISA

Conjugate

Unconjugated

Cat no : 16759-1-AP

Synonyms

HsT18880, IGDCC3, PUNC

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Validation Data Gallery

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  IP experiment of human placenta using 16759-1-AP

  IP result of anti-IGDCC3 (IP:16759-1-AP, 4ug; Detection:16759-1-AP 1:300) with human placenta tissue lysate 1200 ug.

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Tested Applications

• Positive IP detected in: human placenta tissue

Recommended dilution

• Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

16759-1-AP targets IGDCC3 in IP, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: IGDCC3 fusion protein Ag10276
• Full Name: immunoglobulin superfamily, DCC subclass, member 3
• Calculated Molecular Weight: 814 aa, 87 kDa
• Observed Molecular Weight: 87 kDa
• GenBank Accession Number: BC067107
• Gene Symbol: IGDCC3
• Gene ID (NCBI): 9543
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

IGDCC3, also known as PUNC, is a transmembrane protein that belongs to the immunoglobulin (Ig) superfamily (PMID: 9507132). IGDCC3 contains 4 C2-type Ig-like domains and 2 fibronectin type III repeats. It is highly expressed in the developing embryo in nervous system, limbs, and inner ear (PMID: 9922388; 9507132). IGDCC3 may be involved in the cerebellar control of motor coordination (PMID: 11486040). It has also been associated with tumorigenic mechanism and prognosis of cholangiocarcinoma (PMID: 36979826).