IFN Alpha Polyclonal antibody

IFN Alpha Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IF, IHC, ELISA

Conjugate

Unconjugated

Cat no : 18013-1-AP

Synonyms

IFL, IFN, IFN ALPHA, IFN alpha 1/13, IFNA@, IFNA1, IFNA13, IFN-alpha, Interferon alpha 1/13, Interferon alpha D, interferon, alpha 1, Interferon-α1, LeIF D



Tested Applications

Positive WB detected inRecombinant protein

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 18013-1-AP is IFN Alpha Fusion Protein expressed in E. coli.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen IFN Alpha fusion protein Ag12533
Full Name IFNA1
Calculated Molecular Weight 189 aa, 22 kDa
GenBank Accession NumberBC074928
Gene Symbol IFN alpha1
Gene ID (NCBI) 3439
RRIDAB_2878481
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

IFNA1 (IFN-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells, T-helper cells (Th cells), cDCs and natural killer cells (NK cells). IFN-alpha induces B cell maturation into plasma cells and immunoglobulin production. IFN-alpha plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). IFN-alpha was the first cytokine to show clinical benefit in the treatment of certain types of cancer, including melanoma, chronic myelogenous leukemia, and renal cancer.

Protocols

Product Specific Protocols
WB protocol for IFN Alpha antibody 18013-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

J Immunother Cancer

Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma.

Authors - Yuwei Deng
human

mBio

Early enterovirus translation deficits extend viral RNA replication and elicit sustained MDA5-directed innate signaling

Authors - Mikhail I Dobrikov
humanIF

Ann Allergy Asthma Immunol

Lower viral loads in subjects with rhinovirus-challenged allergy despite reduced innate immunity.

Authors - Xin Feng
humanWB

Dig Liver Dis

Innate and adaptive immunity in self-reported nonceliac gluten sensitivity versus celiac disease.

Authors - Antonio Di Sabatino
humanIHC,IF

Clin Oral Investig

Hypermethylation of IFN-γ in oral cancer tissues.

Authors - Songbo Tian
humanWB

Lung

Anti-inflammatory Properties of the Alpha-Melanocyte-Stimulating Hormone in Models of Granulomatous Inflammation.

Authors - Abdolrazagh Hashemi Shahraki